Title : Nrf2, not the estrogen receptor, mediates catechol estrogen-induced activation of the antioxidant responsive element.

Pub. Date : 2003 Oct 1

PMID : 14522084






2 Functional Relationships(s)
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1 Since 4-hydroxyestradiol-induced ARE activation was not inhibited by either 17beta-estradiol or tamoxifen, and overexpression of ER-alpha decreased 4-hydroxyestradiol-induced ARE activation, ARE activation by catechol estrogen was independent of ER. catechol estrogen receptor 1 Homo sapiens
2 Since 4-hydroxyestradiol-induced ARE activation was not inhibited by either 17beta-estradiol or tamoxifen, and overexpression of ER-alpha decreased 4-hydroxyestradiol-induced ARE activation, ARE activation by catechol estrogen was independent of ER. catechol estrogen receptor 1 Homo sapiens