Title : A common polymorphism in the oxygen-dependent degradation (ODD) domain of hypoxia inducible factor-1alpha (HIF-1alpha) does not impair Pro-564 hydroxylation.

Pub. Date : 2003 Sep 9

PMID : 14521712






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Under normoxic conditions, the alpha subunit of HIF is rapidly degraded in a manner dependent on hydroxylation of two conserved proline residues at positions 402 and 564 in HIF-1alpha in the oxygen-dependent degradation (ODD) domain. Proline hypoxia inducible factor 1 subunit alpha Homo sapiens