Title : Increased NF-kappaB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cells.

Pub. Date : 2003 Oct 6

PMID : 14520472






1 Functional Relationships(s)
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1 This indicates that NF-kappaB activated by NS-398 is transcriptionally inactive and is an encouraging result for the use of COX-2-selective NSAIDs not only in chemoprevention but also as novel therapies for colon cancer. Nitrogen mitochondrially encoded cytochrome c oxidase II Homo sapiens