Title : Angiotensin-converting enzyme inhibition modulates high-glucose-induced extracellular matrix changes in mouse glomerular epithelial cells.

Pub. Date : 2003

PMID : 14520012






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Enalaprilat decreased the fibronectin mRNA synthesis dramatically (>50%, p < 0.0001) under high-glucose conditions. Enalaprilat fibronectin 1 Mus musculus
2 CONCLUSIONS: Enalaprilat normalizes the abnormal, high-glucose-induced concentration of laminin, while it decreases the fibronectin synthesis. Enalaprilat fibronectin 1 Mus musculus