Title : Tyrosine kinases inhibitors block Fas-mediated deleterious effects in normoxic and hypoxic ventricular myocytes.

Pub. Date : 2003 Oct

PMID : 14519433






1 Functional Relationships(s)
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1 The major findings were that genistein prevented Fas-mediated increase in 1,4,5-IP(3) production in NRVM (quantified by ion-exchange chromatography): 216 +/- 41 counts per minute (cpm) in control, 605 +/- 184 cpm in FasL-treated cardiomyocytes and 137 +/- 51 cpm in rFasL + genistein-treated cultures. ammonium ferrous sulfate Fas ligand (TNF superfamily, member 6) Mus musculus