Title : Initiator-promoter coupling of phospholipases D and A2 in platelets upon cholesterol incorporation.

Pub. Date : 1992 Dec 7

PMID : 1451798






1 Functional Relationships(s)
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1 We demonstrate here that membrane cholesterol initiates the activation of phosphatidyl choline phospholipase D and phosphatidic acid thus generated promotes the activation of its phospholipase A2 in the presence of extraplatelet calcium. Phosphatidylcholines phospholipase A2 group IB Homo sapiens