Title : On the mechanism of thrombin-induced angiogenesis: inhibition of attachment of endothelial cells on basement membrane components.

Pub. Date : 1998

PMID : 14517385






2 Functional Relationships(s)
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1 The transduction mechanism involved in this action of thrombin seems to be via cAMP, since forskolin or the phosphodiesterase inhibitor 3-isobutyl-1-methyl-xanthine restored the ability of HUVECs that had been exposed to thrombin to adhere. Colforsin coagulation factor II, thrombin Homo sapiens
2 The transduction mechanism involved in this action of thrombin seems to be via cAMP, since forskolin or the phosphodiesterase inhibitor 3-isobutyl-1-methyl-xanthine restored the ability of HUVECs that had been exposed to thrombin to adhere. Colforsin coagulation factor II, thrombin Homo sapiens