Pub. Date : 2003 Oct 7
PMID : 14516190
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RNA-ligand interactions: affinity and specificity of aminoglycoside dimers and acridine conjugates to the HIV-1 Rev response element. | Aminoglycosides | Rev | Human immunodeficiency virus 1 |
| 2 | Semisynthetic aminoglycoside derivatives may provide a means to selectively target viral RNA sites, including the HIV-1 Rev response element (RRE). | Aminoglycosides | Rev | Human immunodeficiency virus 1 |
| 3 | All the modified aminoglycosides exhibit a high affinity for the Rev binding site on the RRE (K(d) <or= 10 nM), but few compounds have a high specificity for the RRE. | Aminoglycosides | Rev | Human immunodeficiency virus 1 |