Title : Comparative pharmacology of the activity of wild-type and G551D mutated CFTR chloride channel: effect of the benzimidazolone derivative NS004.

Pub. Date : 2003 Jul 15

PMID : 14502435






1 Functional Relationships(s)
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1 However, in the presence of 10 microM forskolin, NS004 stimulated G551D-CFTR activity in a dose-dependent manner with an EC(50) approximately 1.5 microM. Colforsin cystic fibrosis transmembrane conductance regulator Cricetulus griseus