Pub. Date : 1992 Dec 5
PMID : 1447187
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Interleukin-1 alpha mediates an alternative pathway for the antiproliferative action of poly(I.C) on human endothelial cells. | Poly I-C | interleukin 1 alpha | Homo sapiens |
| 2 | In addition, the mRNA levels for the cytokines interleukin-1 alpha (IL-1 alpha) and interferon-beta 1 are induced in poly(I.C)-treated cells. | Poly I-C | interleukin 1 alpha | Homo sapiens |
| 3 | In addition, the mRNA levels for the cytokines interleukin-1 alpha (IL-1 alpha) and interferon-beta 1 are induced in poly(I.C)-treated cells. | Poly I-C | interleukin 1 alpha | Homo sapiens |
| 4 | Moreover, the growth inhibitory effects of poly(I.C) are relieved when cells are grown in the presence of an IL-1 alpha antisense oligonucleotide to the human IL-1 alpha transcript. | Poly I-C | interleukin 1 alpha | Homo sapiens |
| 5 | Moreover, the growth inhibitory effects of poly(I.C) are relieved when cells are grown in the presence of an IL-1 alpha antisense oligonucleotide to the human IL-1 alpha transcript. | Poly I-C | interleukin 1 alpha | Homo sapiens |
| 6 | Thus, the effects of poly(I.C) appear to be mediated, in part, through the function of IL-1 alpha, suggesting an alternative pathway for dsRNA-mediated inhibition of human endothelial cell growth. | Poly I-C | interleukin 1 alpha | Homo sapiens |