Pub. Date : 1992 Jul
PMID : 1442930
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Transforming growth factor-beta opposes the stimulatory effects of interleukin-1 and tumor necrosis factor on amnion cell prostaglandin E2 production: implication for preterm labor. | Dinoprostone | transforming growth factor beta 1 | Homo sapiens |
| 2 | We studied the effect of transforming growth factor-beta on the cytokine-induced prostaglandin E2 production by amnion cells. | Dinoprostone | transforming growth factor beta 1 | Homo sapiens |
| 3 | RESULTS: Transforming growth factor-beta decreased the interleukin-1- or tumor necrosis factor-induced prostaglandin E2 production by 70% to 80% and the basal prostaglandin E2 synthesis by 27%. | Dinoprostone | transforming growth factor beta 1 | Homo sapiens |
| 4 | RESULTS: Transforming growth factor-beta decreased the interleukin-1- or tumor necrosis factor-induced prostaglandin E2 production by 70% to 80% and the basal prostaglandin E2 synthesis by 27%. | Dinoprostone | transforming growth factor beta 1 | Homo sapiens |
| 5 | The synergistic stimulation of prostaglandin E2 production by the combination of interleukin-1 with tumor necrosis factor was inhibited by 80% in cells treated with transforming growth factor-beta. | Dinoprostone | transforming growth factor beta 1 | Homo sapiens |
| 6 | CONCLUSION: Transforming growth factor-beta suppresses the cytokine-induced prostaglandin E2 production by amnion cells and may be an important factor in maintaining pregnancy in the face of labor-promoting cytokines. | Dinoprostone | transforming growth factor beta 1 | Homo sapiens |