Pub. Date : 1992 Aug
PMID : 1431598
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Differing effects of cholesterol and taurocholate on steady state hepatic HMG-CoA reductase and cholesterol 7 alpha-hydroxylase activities and mRNA levels in the rat. | Taurocholic Acid | cytochrome P450 family 7 subfamily A member 1 | Rattus norvegicus |
| 2 | Cholesterol 7 alpha-hydroxylase activity increased 4-fold with cholestyramine and 29% during cholesterol feeding, but decreased 64% with taurocholate. | Taurocholic Acid | cytochrome P450 family 7 subfamily A member 1 | Rattus norvegicus |
| 3 | Cholesterol 7 alpha-hydroxylase mRNA levels rose 150% and 50% with cholestyramine and cholesterol feeding, respectively, but decreased 73% with taurocholate. | Taurocholic Acid | cytochrome P450 family 7 subfamily A member 1 | Rattus norvegicus |
| 4 | The administration of cholesterol together with taurocholate prevented the decline in cholesterol 7 alpha-hydroxylase mRNA levels, but inhibition of enzyme activity persisted (-76%). | Taurocholic Acid | cytochrome P450 family 7 subfamily A member 1 | Rattus norvegicus |