Title : Assay of intracellular thymidylate synthetase activity and inhibition by 5-fluoro-2'-deoxyuridine in lymphocytes.

Pub. Date : 1992 Aug

PMID : 1430788






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Thymidylate synthetase catalyses the formation of thymidine monophosphate from deoxyuridine monophosphate. 2'-deoxyuridylic acid thymidylate synthetase Homo sapiens
2 Purified thymidylate synthetase can be assayed radiochemically using labelled deoxyuridine monophosphate as substrate, but cells are impervious to deoxyuridine monophosphate and so intracellular thymidylate synthetase activity cannot be assayed in this way. 2'-deoxyuridylic acid thymidylate synthetase Homo sapiens