Pub. Date : 1992 Dec 1
PMID : 1423295
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | injection of 300 microCi 131I-labeled MB-1 (IgG1) was compared to treatment with unlabeled MB-1 or 300 microCi 131I-labeled MYS control IgG1 MoAb, an antibody-specific targeted radiation effect of RIT was seen. | Iodine-131 | CD79a molecule | Homo sapiens |
| 2 | 131I-labeled MB-1 produced a 44 +/- 19% (SEM) reduction in tumor size at 3 weeks posttreatment, while unlabeled MB-1 or 300 microCi 131I-labeled MYS control IgG1 antibody treatment resulted in continued tumor growth over this period of time. | Iodine-131 | CD79a molecule | Homo sapiens |
| 3 | Similar to the MB-1 studies, treatment with 300 microCi 131I-labeled anti-B1 produced a 64% reduction in mean tumor size, while 300 microCi of control antibody resulted in a 58% increase in tumor size over the same 3-week period. | Iodine-131 | CD79a molecule | Homo sapiens |
| 4 | In contrast, antibody-specific targeting of radiation was the dominant mechanism of tumor killing with 131I-labeled MB-1. | Iodine-131 | CD79a molecule | Homo sapiens |