Title : An improved fluorometric assay for dosimetry of benzo(a)pyrene diol-epoxide-DNA adducts in smokers' lung: comparisons with total bulky adducts and aryl hydrocarbon hydroxylase activity.

Pub. Date : 1992 Nov 15

PMID : 1423269






1 Functional Relationships(s)
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1 A highly significant correlation was found between pulmonary microsomal aryl hydrocarbon hydroxylase activity and the level of benzo(a)pyrene diolepoxide-DNA adduct (r = 0.91; P < 0.001; n = 13). 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide cytochrome P450 family 1 subfamily B member 1 Homo sapiens