Title : Binding study of metal ions to S100 protein: 43Ca, 25Mg, 67Zn and 39K n.m.r.

Pub. Date : 1992 Oct

PMID : 1419966






4 Functional Relationships(s)
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1 The interactions of the S100 protein (S100) with metal cations such as Ca2+, Mg2+, Zn2+ and K+ were studied by the metal n.m.r. Zinc S100 calcium binding protein B Homo sapiens
2 The interactions of the S100 protein (S100) with metal cations such as Ca2+, Mg2+, Zn2+ and K+ were studied by the metal n.m.r. Zinc S100 calcium binding protein B Homo sapiens
3 of the Zn(2+)-S100 solutions. Zinc S100 calcium binding protein B Homo sapiens
4 These findings suggest that: (1) Mg2+ binds to all S100s, and at least one of the Mg2+ binding sites of S100 molecule is the same as the Ca2+ binding site; (2) Zn2+ binds to S100s, although the binding site(s) is/are different from Ca(2+)- or Mg(2+)-binding site(s), and the environment of Zn2+ nuclei will not change even though Ca2+ binds to S100s. Zinc S100 calcium binding protein B Homo sapiens