Title : Glutathione S-transferase activity and isoenzyme composition in benign ovarian tumours, untreated malignant ovarian tumours, and malignant ovarian tumours after platinum/cyclophosphamide chemotherapy.

Pub. Date : 1992 Nov

PMID : 1419639






3 Functional Relationships(s)
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1 Glutathione S-transferase activity and isoenzyme composition in benign ovarian tumours, untreated malignant ovarian tumours, and malignant ovarian tumours after platinum/cyclophosphamide chemotherapy. Cyclophosphamide glutathione S-transferase kappa 1 Homo sapiens
2 GST isoenzyme patterns were identical in benign tumours and malignant tumours before and after platinum/cyclophosphamide chemotherapy, while GST pi was the predominant transferase. Cyclophosphamide glutathione S-transferase kappa 1 Homo sapiens
3 Mean GST activity and GST pi amount were decreased (P < 0.05) in malignant ovarian tumours after platinum/cyclophosphamide chemotherapy compared to untreated ovarian malignant tumours. Cyclophosphamide glutathione S-transferase kappa 1 Homo sapiens