Title : Suppression of interleukin-2 and interleukin-2 receptor expression in Jurkat cells stably expressing the human immunodeficiency virus Tat protein.

Pub. Date : 1992 Oct 1

PMID : 1394441






1 Functional Relationships(s)
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1 After stimulation with phytohemagglutinin (PHA) and phorbol myristate acetate (PMA), Tat transfectants with high Tat expression showed diminished expression of interleukin-2 (IL-2) and the interleukin-2 receptor alpha chain (IL-2R) when compared to untransfected Jurkat cells or Jurkat cell lines transfected with the parent control plasmid. Tetradecanoylphorbol Acetate interleukin 2 receptor subunit alpha Homo sapiens