Title : Regulation of progesterone secretion in human syncytiotrophoblast in culture by human chorionic gonadotropin.

Pub. Date : 1992 May

PMID : 1376614






4 Functional Relationships(s)
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1 When the cells were challenged with dibutryl cAMP (dbcAMP), forskolin or isobutylmethylxanthine, they produced significantly higher amounts of progesterone which in the presence of the hCG antibody was reduced to the level of the control set of cells. Bucladesine chorionic gonadotropin subunit beta 5 Homo sapiens
2 Neutralization of hCG by the antibodies, however, drastically reduced the LDL induced progesterone secretion, which was restored by the addition of dbcAMP to the medium. Bucladesine chorionic gonadotropin subunit beta 5 Homo sapiens
3 Since dbcAMP could mimic these actions of hCG, the data suggest a possible autocrine/paracrine role of hCG on the trophoblast cells. Bucladesine chorionic gonadotropin subunit beta 5 Homo sapiens
4 Since dbcAMP could mimic these actions of hCG, the data suggest a possible autocrine/paracrine role of hCG on the trophoblast cells. Bucladesine chorionic gonadotropin subunit beta 5 Homo sapiens