Pub. Date : 1992 May
PMID : 1374948
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | FK506 pretreatment significantly reduced the serum levels of BUN (P less than 0.02), creatinine (P less than 0.02), and TNF (P less than 0.05) as compared with that seen in controls. | Tacrolimus | tumor necrosis factor | Rattus norvegicus |
2 | Based upon these data, it can be concluded that (1) FK506 pretreatment ameliorates the functional renal injury associated with I/R, (2) renal ischemia induces the release of TNF, and (3) FK506 pretreatment results in a significant inhibition of TNF production. | Tacrolimus | tumor necrosis factor | Rattus norvegicus |
3 | Based upon these data, it can be concluded that (1) FK506 pretreatment ameliorates the functional renal injury associated with I/R, (2) renal ischemia induces the release of TNF, and (3) FK506 pretreatment results in a significant inhibition of TNF production. | Tacrolimus | tumor necrosis factor | Rattus norvegicus |