Pub. Date : 1992 Feb 28
PMID : 1371921
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of IgE-mediated histamine release by myosin light chain kinase inhibitors. | Histamine | myosin light chain kinase | Rattus norvegicus |
| 2 | Wortmannin, a specific inhibitor of myosin light chain kinase (MLCK) blocked IgE mediated histamine release from rat basophilic leukemia cell (RBL-2H3) and human basophils dose-dependently. | Histamine | myosin light chain kinase | Rattus norvegicus |
| 3 | Wortmannin, a specific inhibitor of myosin light chain kinase (MLCK) blocked IgE mediated histamine release from rat basophilic leukemia cell (RBL-2H3) and human basophils dose-dependently. | Histamine | myosin light chain kinase | Rattus norvegicus |
| 4 | KT5926, another MLCK inhibitor, inhibited histamine release comparably with wortmannin and blocked to some degree the increase of [Ca2+]i in RBL-2H3 cells. | Histamine | myosin light chain kinase | Rattus norvegicus |