Title : Effects of FK506 and cyclosporin A on cytokine production studied in vitro at a single-cell level.

Pub. Date : 1992 Jan

PMID : 1371491






1 Functional Relationships(s)
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1 When the cells were stimulated by phorbol ester (phorbol 12-myristate 13-acetate, PMA) plus calcium ionophore (ionomycin), FK506 and CsA inhibited, in a dose-dependent manner, the production of IL-2, IL-4, IL-5, IFN-gamma and TNF-alpha. Ionomycin interleukin 5 Homo sapiens