Title : Primary sequences of two P-glycoprotein genes of Entamoeba histolytica.

Pub. Date : 1992 Sep

PMID : 1359408






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Within each ameba P-glycoprotein were the ATP-binding sites found twice in eukaryotic P-glycoproteins and once in prokaryotic transport proteins. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens
2 Hydropathy plots of the ameba P-glycoproteins were nearly superimposable on that of the human mdr 1, showing 2 homologous halves, each containing an ATP-binding site and 6 hydrophobic transmembrane domains that form the putative channel. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens
3 Also identified in the E. histolytica genomic library were 2 P-glycoprotein pseudogenes, each with a frame shift and stop codons in identical places within the amino ATP-binding site. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens