Title : N-methyl-D-aspartate antagonists block fos-like protein expression induced via multiple signaling pathways in cultured cortical neurons.

Pub. Date : 1992 May

PMID : 1348524






3 Functional Relationships(s)
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1 c-fos mRNA and Fos-like protein(s) (FLP) are induced in cultured cortical neurons by glutamate, high K+, phorbol ester, basic fibroblast growth factor, Zn2+, and vasoactive intestinal peptide. Phorbol Esters Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 c-fos mRNA and Fos-like protein(s) (FLP) are induced in cultured cortical neurons by glutamate, high K+, phorbol ester, basic fibroblast growth factor, Zn2+, and vasoactive intestinal peptide. Phorbol Esters Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
3 These antagonists partially block high K(+)-, phorbol ester-, Zn(2+)-, and VIP-induced c-fos mRNA expression, but have no effect on bFGF-induced c-fos mRNA expression. Phorbol Esters Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens