Pub. Date : 1992 Dec
PMID : 1336317
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The inotropic response induced by isoproterenol (isoprenaline, 20 ng.kg-1 x min-1), measured by m-mode echocardiography as the increase of fractional shortening in seven healthy subjects, was reduced from 17.1 +/- 4.3 to 9.1 +/- 3.9% (P < 0.01) by M-cholinoceptor stimulation using intravenous injection of 3.6 micrograms/kg carbachol. | Isoproterenol | CD59 molecule (CD59 blood group) | Homo sapiens |
2 | The inotropic response induced by isoproterenol (isoprenaline, 20 ng.kg-1 x min-1), measured by m-mode echocardiography as the increase of fractional shortening in seven healthy subjects, was reduced from 17.1 +/- 4.3 to 9.1 +/- 3.9% (P < 0.01) by M-cholinoceptor stimulation using intravenous injection of 3.6 micrograms/kg carbachol. | Isoproterenol | CD59 molecule (CD59 blood group) | Homo sapiens |
3 | However, the inotropic response of increasing doses of isoprenaline (5-20 ng.kg-1 x min-1) did not differ in 13 healthy subjects without and after M-cholinoceptor blockade (atropine, 0.015 mg/kg i.v. | Isoproterenol | CD59 molecule (CD59 blood group) | Homo sapiens |
4 | ); the increase of fractional shortening amounted to 17.4 +/- 4.0 vs. 19.5 +/- 4.8% (NS) in response to 20 ng.kg-1 x min-1 isoprenaline. | Isoproterenol | CD59 molecule (CD59 blood group) | Homo sapiens |