Title : Actions of thapsigargin on the Ca(2+)-handling systems of the human platelet. Incomplete inhibition of the dense tubular Ca2+ uptake, partial inhibition of the Ca2+ extrusion pump, increase in plasma membrane Ca2+ permeability, and consequent elevation of resting cytoplasmic Ca2+.

Pub. Date : 1992 Dec 15

PMID : 1334075






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Thrombin and Tg release 30 and 70% (respectively) of the DT Ca2+ available at any instant, independent of order of challenge, consistent with a single class of DT with respect to these agents. Thymidine coagulation factor II, thrombin Homo sapiens
2 Thrombin and Tg release 30 and 70% (respectively) of the DT Ca2+ available at any instant, independent of order of challenge, consistent with a single class of DT with respect to these agents. Thymidine coagulation factor II, thrombin Homo sapiens