Title : Synthesis of tissue inhibitor of metalloproteinase-1 (TIMP-1) in human hepatoma cells (HepG2). Up-regulation by interleukin-6 and transforming growth factor beta 1.

Pub. Date : 1992 Nov 23

PMID : 1330702






1 Functional Relationships(s)
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1 We show at mRNA and protein levels that TIMP-1 is expressed in differentiated human hepatoma cells (HepG2) and that its synthesis is up-regulated by interleukin-6 (IL-6), transforming growth factor beta 1 and phorbol 12-myristate 13-acetate. Tetradecanoylphorbol Acetate TIMP metallopeptidase inhibitor 1 Homo sapiens