Title : Nitric oxide formation caused by Ca2+ release from internal stores in neuronal cell line is enhanced by cyclic AMP.

Pub. Date : 1992 Sep 1

PMID : 1330642






3 Functional Relationships(s)
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1 Maximal amplitude and duration of cyclic GMP response to bradykinin were about 2-fold greater in cells with cyclic AMP levels increased by forskolin pretreatment than in control cells with basal levels of cyclic AMP. Colforsin 5'-nucleotidase, cytosolic II Homo sapiens
2 The cyclic GMP responses to bradykinin were suppressed with the same potency by L-arginine analogues in control and in forskolin-treated cells (IC50 of NG-monomethyl-L-arginine 2 microM, of nitro-L-arginine 0.7 microM). Colforsin 5'-nucleotidase, cytosolic II Homo sapiens
3 The transient rises of cyclic GMP levels induced by bradykinin and endothelin, which both cause release of Ca2+ from internal stores, were similarly enhanced by forskolin pretreatment. Colforsin 5'-nucleotidase, cytosolic II Homo sapiens