Title : Effect of retinoid status on alpha, beta and gamma retinoic acid receptor mRNA levels in various rat tissues.

Pub. Date : 1992 Sep 15

PMID : 1329717






4 Functional Relationships(s)
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1 Retinol also restored the RAR beta mRNA level, but the magnitude and kinetics of the induction differed from those by retinoic acid. Vitamin A retinoic acid receptor, beta Rattus norvegicus
2 In addition, from these results it was postulated that the maintenance of the normal RAR beta mRNA levels seemed to require a threshold serum retinol concentration (about 25 micrograms/dl). Vitamin A retinoic acid receptor, beta Rattus norvegicus
3 Moreover, we found that administration of retinol and retinoic acid to normal rats caused the overexpression of RAR beta transcripts (2-15-fold) when compared with the control levels of RAR beta mRNA, although the levels of RAR alpha and RAR gamma mRNAs were not affected. Vitamin A retinoic acid receptor, beta Rattus norvegicus
4 Moreover, we found that administration of retinol and retinoic acid to normal rats caused the overexpression of RAR beta transcripts (2-15-fold) when compared with the control levels of RAR beta mRNA, although the levels of RAR alpha and RAR gamma mRNAs were not affected. Vitamin A retinoic acid receptor, beta Rattus norvegicus