Title : Oxygen-derived free radical and active oxygen complex formation from cobalt(II) chelates in vitro.

Pub. Date : 1992 Jan-Feb

PMID : 1316186






2 Functional Relationships(s)
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1 The electron paramagnetic resonance (EPR) spin trapping technique was used to study the generation of oxygen free radicals from the reaction of hydrogen peroxide with various Co(II) complexes in pH 7.4 phosphate buffer. Oxygen mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 In the presence of ethylenediamine, Co(II) bound molecular O2 and directly oxidized DMPO to its DMPO/.OH adduct without first forming free superoxide, hydroxyl radical, or hydrogen peroxide. Oxygen mitochondrially encoded cytochrome c oxidase II Homo sapiens