Pub. Date : 1992 Apr 25
PMID : 1314821
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Spin trapping evidence for myeloperoxidase-dependent hydroxyl radical formation by human neutrophils and monocytes. | Hydroxyl Radical | myeloperoxidase | Homo sapiens |
| 2 | Detection of hydroxyl radical from stimulated monocyte-derived macrophages, which lack myeloperoxidase, required the addition of supplemental iron. | Hydroxyl Radical | myeloperoxidase | Homo sapiens |
| 3 | The addition of purified myeloperoxidase to an enzymatic superoxide generating system resulted in the detection of hydroxyl radical that was dependent upon the presence of chloride and was inhibited by superoxide dismutase, catalase, and azide. | Hydroxyl Radical | myeloperoxidase | Homo sapiens |
| 4 | 4-POBN-CH(CH3)OH was not observed upon stimulation of myeloperoxidase-deficient neutrophils, whereas addition of myeloperoxidase to the reaction mixture resulted in the detection of hydroxyl radical. | Hydroxyl Radical | myeloperoxidase | Homo sapiens |
| 5 | These results support the ability of human neutrophils and monocytes to generate hydroxyl radical through a myeloperoxidase-dependent mechanism. | Hydroxyl Radical | myeloperoxidase | Homo sapiens |