Title : Antisense therapy targeting MDM2 oncogene in prostate cancer: Effects on proliferation, apoptosis, multiple gene expression, and chemotherapy.

Pub. Date : 2003 Sep 30

PMID : 13130078






1 Functional Relationships(s)
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1 In all three cell lines, MDM2 inhibition reduced cell proliferation, induced apoptosis, and potentiated the effects of the chemotherapeutic agents 10-hydroxycamptothecin and paclitaxel. 10-hydroxycamptothecin MDM2 proto-oncogene Homo sapiens