Title : Increased hypothalamic [3H]flunitrazepam binding in hypothalamic-pituitary-adrenal axis hyporesponsive Lewis rats.

Pub. Date : 1992 Jan 13

PMID : 1311618






1 Functional Relationships(s)
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1 Since benzodiazepines attenuate hypothalamic CRH secretion through GABAergic inhibition, we suggest that strain differences in receptor number could also augment strain differences in hypothalamic-pituitary-adrenal axis function through differential sensitivity to GABA-mediated feedback. Benzodiazepines corticotropin releasing hormone Rattus norvegicus