Title : Low frequency of p53 gene mutation in tumors induced by aflatoxin B1 in nonhuman primates.

Pub. Date : 1992 Feb 15

PMID : 1310637






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Low frequency of p53 gene mutation in tumors induced by aflatoxin B1 in nonhuman primates. Aflatoxin B1 tumor protein p53 Homo sapiens
2 Aflatoxin B1 has been suggested as a causative agent for a G to T mutation at codon 249 in the p53 gene in human hepatocellular carcinomas from southern Africa and Qidong in China. Aflatoxin B1 tumor protein p53 Homo sapiens
3 The occurrence of mutation in codon 249 of the p53 gene in selective samples of human hepatocellular cancers may indicate involvement of environmental carcinogens other than aflatoxin B1 or that hepatitis B virus-related hepatitis is a prerequisite for aflatoxin B1 induction of G to T transversion in codon 249. Aflatoxin B1 tumor protein p53 Homo sapiens