Title : Direct identification of lysine-33 as the principal cationic center of the omega-amino acid binding site of the recombinant kringle 2 domain of tissue-type plasminogen activator.

Pub. Date : 1992 Jan

PMID : 1309292






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We have generated site-specific mutants of the kringle 2 domain of tissue-type plasminogen activator [( K2tPA]) in order to identify directly the cationic center of the protein that is responsible for its interaction with the carboxyl group of important omega-amino acid effector molecules, such as epsilon-amino caproic acid (EACA). Aminocaproic Acid plasminogen activator, tissue type Homo sapiens