Title : S-adenosylmethionine decarboxylase as an enzyme target for therapy.

Pub. Date : 1992 Dec

PMID : 1301596






1 Functional Relationships(s)
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1 Recently, powerful irreversible inhibitors of AdoMetDC have become available including 5"-([(Z)-4-amino-2-butenyl]methylamino)-5"-deoxyadenosine, an enzyme activated inhibitor and 5"-deoxy-5"-[(3-hydrazinopropyl)methylamino]adenosine which binds to the active site and forms a covalent bond with the pyruvate prosthetic group. Pyruvic Acid adenosylmethionine decarboxylase 1 Homo sapiens