Title : Perspectives in the treatment of Parkinson's disease: COMT inhibitors open up new treatment strategies.

Pub. Date : 1999 Sep

PMID : 12973467






1 Functional Relationships(s)
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1 Entacapone is a potent, selective peripheral catechol O-methyltransferase inhibitor which effectively inhibits the O-methylation of levodopa, thus increasing its central bioavailability and potentiating its behavioral effects. entacapone catechol-O-methyltransferase Homo sapiens