Title : Cytochrome P450 2C8 and CYP3A4/5 are involved in chloroquine metabolism in human liver microsomes.

Pub. Date : 2003 Aug

PMID : 12967198






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 It is metabolized in humans through the N-dealkylation pathway, to desethylchloroquine (DCQ) and bisdesethylchloroquine (BDCQ), by cytochrome P450 (CYP). Nitrogen cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 It is metabolized in humans through the N-dealkylation pathway, to desethylchloroquine (DCQ) and bisdesethylchloroquine (BDCQ), by cytochrome P450 (CYP). Nitrogen cytochrome P450 family 4 subfamily F member 3 Homo sapiens