Title : Preventive effect of bis-eugenol, a eugenol ortho dimer, on lipopolysaccharide-stimulated nuclear factor kappa B activation and inflammatory cytokine expression in macrophages.

Pub. Date : 2003 Sep 15

PMID : 12963494






1 Functional Relationships(s)
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1 We observed that bis-eugenol, but not eugenol, clearly inhibited the degradation of inhibitory kappa B-alpha in RAW264.7 murine macrophages stimulated with lipopolysaccharide and, consequently, the transcriptional activity of the stimulated NF-kappa B in the cells. Eugenol nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus