Title : Early and reversible neuropathology induced by tetracycline-regulated lentiviral overexpression of mutant huntingtin in rat striatum.

Pub. Date : 2003 Nov 1

PMID : 12952868






1 Functional Relationships(s)
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1 In contrast, expression of a shorter htt form (htt171-82Q) did not require processing prior formation of nuclear aggregates and caused decrease of both DARPP-32 and NeuN neuronal markers at one month post-injection suggesting that polyQ pathology may be dependent on protein context. polyglutamine huntingtin Rattus norvegicus