Title : A dynamic constitutive and inducible binding of c-Cbl by PLCgamma1 SH3 and SH2 domains (negatively) regulates antigen receptor-induced PLCgamma1 activation in lymphocytes.

Pub. Date : 2003 Sep 10

PMID : 12941616






1 Functional Relationships(s)
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1 Additional data indicate that the SH3 domain of PLCgamma1 binds to both canonical and noncanonical SH3 domain-binding sites in the proline-rich region of c-Cbl. Proline Cbl proto-oncogene Homo sapiens