Title : All-trans retinoic acid modulates microvascular endothelial cell hemostatic properties.

Pub. Date : 2003 Aug

PMID : 12935977






3 Functional Relationships(s)
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1 RESULTS: ATRA significantly inhibited TNFalpha-induced TF expression in HMEC-1 as well as HUVEC. Tretinoin tumor necrosis factor Homo sapiens
2 ATRA increased t-PA antigen without significantly affecting PAI-1 expression, and counteracted the TNFalpha-induced t-PA decrease in both types of EC. Tretinoin tumor necrosis factor Homo sapiens
3 Finally, ATRA upregulated TM, and prevented TNFalpha-induced TM downregulation. Tretinoin tumor necrosis factor Homo sapiens