Title : A mouse model of Rubinstein-Taybi syndrome: defective long-term memory is ameliorated by inhibitors of phosphodiesterase 4.

Pub. Date : 2003 Sep 2

PMID : 12930888






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A critical role for cAMP signaling during CREB-dependent long-term memory formation appears to be evolutionarily conserved. Cyclic AMP cAMP responsive element binding protein 1 Mus musculus
2 From this observation, we reasoned that drugs that modulate CREB function by enhancing cAMP signaling might yield an effective treatment for the memory defect(s) of CBP+/- mice. Cyclic AMP cAMP responsive element binding protein 1 Mus musculus