Title : Prevention of dopaminergic neuronal death by cyclic AMP in mixed neuronal/glial mesencephalic cultures requires the repression of presumptive astrocytes.

Pub. Date : 2003 Sep

PMID : 12920193






3 Functional Relationships(s)
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1 The neuroprotective and antiproliferative actions of cAMP, however, were closely mimicked by olomoucine and roscovitine, potent inhibitors of the cyclin-dependent kinase CDK1 that are structurally related to cAMP. Cyclic AMP cyclin dependent kinase 1 Homo sapiens
2 The neuroprotective and antiproliferative actions of cAMP, however, were closely mimicked by olomoucine and roscovitine, potent inhibitors of the cyclin-dependent kinase CDK1 that are structurally related to cAMP. Cyclic AMP cyclin dependent kinase 1 Homo sapiens
3 Measurement of CDK1 activity confirmed that neuroprotection was closely correlated with inhibition of this kinase by cAMP. Cyclic AMP cyclin dependent kinase 1 Homo sapiens