Title : Induction of apoptosis by takrisodokyeum through generation of hydrogen peroxide and activation of caspase-3 in HL-60 cells.

Pub. Date : 2003 Aug 29

PMID : 12899915






1 Functional Relationships(s)
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1 Taken together, these results suggest that TRSDY induces hydrogen peroxide generation, which, in turn, causes activation of caspase-3, degradation of PARP and D4-GDI, and eventually leads to apoptotic cell death. Hydrogen Peroxide poly(ADP-ribose) polymerase 1 Homo sapiens