Pub. Date : 2003 Aug
PMID : 12891383
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Promoter polymorphism influences the effect of dexamethasone on transcriptional activation of the LTC4 synthase gene. | Dexamethasone | leukotriene C4 synthase | Homo sapiens |
| 2 | Using in vitro transfection of promoter-reporter constructs, dexamethasone was shown to increase transcription of LTC4S by more than 50% for the -1072G/-444A, A-C and G-C haplotype constructs (P&<0.02), but to have no effect on the A-A haplotype (P=0.27). | Dexamethasone | leukotriene C4 synthase | Homo sapiens |