Title : Anthocyanidins induce apoptosis in human promyelocytic leukemia cells: structure-activity relationship and mechanisms involved.

Pub. Date : 2003 Sep

PMID : 12888907






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The efficacious induction of apoptosis was observed at 100 micro M for 6 h. Concomitant with the apoptosis, delphinidin stimulates JNK pathway activation including JNK phosphorylation and c-jun gene expression, and activates caspase-3. delphinidin mitogen-activated protein kinase 8 Homo sapiens
2 The efficacious induction of apoptosis was observed at 100 micro M for 6 h. Concomitant with the apoptosis, delphinidin stimulates JNK pathway activation including JNK phosphorylation and c-jun gene expression, and activates caspase-3. delphinidin mitogen-activated protein kinase 8 Homo sapiens
3 Antioxidants including N-acetyl-L-cysteine (NAC) and catalase effectively block delphinidin-induced JNK phosphorylation, caspase-3 activation, and DNA fragmentation. delphinidin mitogen-activated protein kinase 8 Homo sapiens