Title : Anthocyanidins induce apoptosis in human promyelocytic leukemia cells: structure-activity relationship and mechanisms involved.

Pub. Date : 2003 Sep

PMID : 12888907






1 Functional Relationships(s)
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1 The efficacious induction of apoptosis was observed at 100 micro M for 6 h. Concomitant with the apoptosis, delphinidin stimulates JNK pathway activation including JNK phosphorylation and c-jun gene expression, and activates caspase-3. delphinidin Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens