Pub. Date : 2003 Oct 10
PMID : 12888568
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Iron regulates IRP2 by mediating its rapid proteasomal degradation, where hypoxia and the hypoxia mimetics CoCl2 and desferrioxamine (DFO) stabilize it. | Deferoxamine | iron responsive element binding protein 2 | Homo sapiens |
| 2 | Iron regulates IRP2 by mediating its rapid proteasomal degradation, where hypoxia and the hypoxia mimetics CoCl2 and desferrioxamine (DFO) stabilize it. | Deferoxamine | iron responsive element binding protein 2 | Homo sapiens |
| 3 | In addition, DFO and hypoxia blocked the degradation of both the wild-type and mutant IRP2 proteins. | Deferoxamine | iron responsive element binding protein 2 | Homo sapiens |
| 4 | In addition, hypoxia, DFO and DMOG blocked IRP2 ubiquitination. | Deferoxamine | iron responsive element binding protein 2 | Homo sapiens |