Title : Pathways for the regulation of interferon-gamma-inducible genes by iron in human monocytic cells.

Pub. Date : 2003 Aug

PMID : 12885946






3 Functional Relationships(s)
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1 Addition of iron before cytokine stimulation resulted in a dose-dependent reduction of these pathways, and iron restriction by desferrioxamine (DFO) enhanced ICAM-1, HLA-DR, and GTP-CH expression. Deferoxamine intercellular adhesion molecule 1 Homo sapiens
2 Addition of iron before cytokine stimulation resulted in a dose-dependent reduction of these pathways, and iron restriction by desferrioxamine (DFO) enhanced ICAM-1, HLA-DR, and GTP-CH expression. Deferoxamine intercellular adhesion molecule 1 Homo sapiens
3 IFN-gamma-inducible mRNA expression of ICAM-1, HLA-DR, and GTP-CH was reduced by iron and increased by DFO by a transcriptional mechanism. Deferoxamine intercellular adhesion molecule 1 Homo sapiens